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Assay Ready Cells
  • Healthcare
  • Research

ARC ‐ Assay Ready Cells

AssayWorks, Germany has developed a set of recombinant cell lines expressing pharmaceutically relevant receptors and ion channels. The targets are commonly used for small molecule compound screening, lead identification, and selectivity testing. acCELLerate provides these cell lines in assay ready...

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Assay Ready Cells
  • Healthcare
  • Safety

PRC ‐ Patch Ready Cells (Voltage Gated Ion Channels)

Patch Ready Cells are pre‐qualified aliquots of cryopreserved cells which can be used in patch clamp assays without prior cultivation. The set of cell lines expresses pharmaceutically relevant ion channels including the six cardiac channels of the CiPA panel. The ion channel cell lines have been...

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Biocompatability-Kit
  • Healthcare
  • Safety

instaCELL® Cytotoxicity Assay Kits

instaCELL cytotoxicity assay kits have been designed to improve the reliability and reproducibility of routine toxicity testing. The assay kit includes aliquots of cryopreserved assay ready cells which have been qualified for the testing. The cells can be used like a reagent instantly after thawing...

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G-CSF Potency Assay Kit
  • Healthcare
  • Quality

instaCELL® G-CSF Potency Assay Kit

The instaCELL G-CSF potency assay kit is an in vitro test to determine the potency of Granulocyte Colony Stimulation Factor (G-CSF) formulations for quality control. Recombinant forms of G-CSF are used in medicine to treat conditions associated with neutropenia (a low neutrophil count), such as...

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Micronucleus-Kit
  • Healthcare
  • Cosmetics
  • Chemicals
  • Research
  • Safety

instaCELL® Genotoxicity Assay Kits

Chemicals or other environmental noxes which damage the DNA or interfere with cell division, may impact the genomic integrity of cells. This can result in cell death and cancer. To screen chemicals for their genotoxic and mutagenic potential multiple types of assays have been developed. A cell‐based...

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GM-CSF Potency Assay Kit
  • Healthcare
  • Quality

instaCELL® GM-CSF Potency Assay Kit

The instaCELL GM-CSF potency assay kit is an in vitro test to determine the potency of Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) formulations for quality control. Recombinant forms of GM-CSF are used for white blood cell recovery following autologous bone marrow transplantation or...

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Pyrogen-Detection-Kit-"MAT"
  • Healthcare
  • Safety
  • Research

instaCELL® Pyrogen Detection Kit (MAT)

The monocyte activation test (MAT) is used to detect or quantify substances that activate human monocytes to release endogenous mediators such as pro-inflammatory cytokines like tumor necrosis factor alpha (TNFα) which play an important role in fever pathogenesis. The MAT assay detects the presence...

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Keratinosens-Kit
  • Cosmetics
  • Safety

instaCELL® Skin Sensitization Assay Kits

Allergic contact dermatitis is an environmental health issue induced by chemicals. A set of alternative methods has been approved by the OECD to test potential skin sensitizers in vitro. The cell‐based assays represent early key events of the skin sensitization process. h‐CLAT, the human Cell Line...

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TNFa-neutralization-kit
  • Safety

instaCELL® TNF-α neutralization assay kit

The instaCELL TNF-α neutralization assay kit is used to determine the potency of tumor necrosis factor-alpha (TNF‑α) neutralizing/inhibiting therapeutics. These recombinant antibodies and soluble proteins are used to regulate excessive inflammatory responses in the body. A dysregulation of TNF-a is...

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TNFa-potency-kit
  • Safety

instaCELL® TNF-α potency assay kit

Tumor necrosis factor alpha (TNF-α) is a multifunctional signaling substance involved in local and systemic inflammation. Its primary function is the regulation of various immune cells and is therefore mainly secreted by macrophages. TNF-α can induce fever, apoptotic cell death, cachexia, and...

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